Skip to main content

New Oral Anticoagulants: Specific tests



Rivaroxaban:
Anti-FXa activity
PT and aPTT modified according to the reagent (PT more sensitive)


Apixaban:
Anti-FXa activity
PT and aPTT not really prolonged

Dabigatran:
Ecarin clotting time, Haemoclott or anti-IIa
PT, aPTT and TT modified according to the reagent (aPTT more sensitive)



Ref. MM Samama et al Clin Chem Lab Med 2011;49,761

Comments

  1. Very informative, helpful article. Thank you so much for the research and effort that went into preparing this. You can also check B2BContact Lists to know more about how to reach your target audience at right time and engage with your targeted audience by opting healthcare professional’s contact database.Chief of Anesthesiology Mailing List & Email List

    ReplyDelete
  2. Thanks for this great post! - This provides good insight. You might also be interested to know more about generating more leads and getting the right intelligence to engage prospects.pegasimediagroup implements new lead gen ideas and strategies for generating more leads and targeting the right leads and accounts. Anesthesiology email list

    ReplyDelete
  3. Great article – Impressive: We think you might be interested to know more about our company. helps you get your hands on world’s best class customized B2B Contact List, which can make your sales and marketingcampaigns cost effective. Achieve Your Marketing Goals and Grow Your Business.Use B2B Contact Lists to get better and

    deeperinsights. You and your sales team get to hear true voice of your target audience, much more effectively as comparetoothertraditional market research methodologies.Anesthesiologist Mailing List & Email List

    ReplyDelete
  4. Thanks for this great post!- This provides good insight. You might also be interested to know more about generating more leads and getting the right intelligence to engage prospects.E-Health Care Lists implements new lead gen ideas and strategies for generating more leads and targeting the right leads and accounts.E-Health Care Lists is one of the global suppliers of healthcare mailing list & email list.Marketing to the healthcare industry, reaching the doctors and other healthcare decision makers is often an impossibletask.Chief of Anesthesiology Mailing list & Email list

    ReplyDelete

Post a Comment

Popular posts from this blog

power injectable peripherally inserted central catheters

Clinical experience with power injectable peripherally inserted central catheters in intensive care patients     Introduction In intensive care units (ICU), peripherally inserted central catheters (PICC) may be an alternative option to standard central venous catheters, particularly in patients with coagulation disorders or at high risk for infection. Some limits of PICCs (such as low flow rates) may be overcome by the use of power-injectable catheters . Method We have retrospectively reviewed all the power injectable PICCs inserted in adult and pediatric patients in the ICU during a 12-month period, focusing on the rate of complications at insertion and during maintenance. Results We have collected 89 power injectable PICCs (in adults and in children), both multiple and single lumen. All insertions were successful. There were no major complications at insertion and no episodes of catheter-related blood stream infection. Non-infective complications ...

Things to Avoid in Anesthesia for Pregnant with Pulmonary hypertension

Anesthesia for Pregnant woman with Pulmonary Hypertension is a real challenge for anesthesiologist. It is very crucial to remember the pathophysiology of pulmonary hypertension in pregnant women and to avoid some practices that will worsen the cardiac status. 1-Avoid single shot spinal anesthesia. Some authorities consider pulmonary hypertension as absolute contraindication for single shot spinal anesthesia specially in patients with NYHA III ,IV. Spinal anesthesia causes major hemodynamic instability(decrease SVR, decrease VR, decrease in CO) The preferred neuroaxial techniques are (epidural anesthesia and CSE with minimal spinal dose) 2-Avoid PAC. Pulmonary Artery catheters insertion may lead to pulmonary artery rupture or thrombosis. TEE is better cardiac monitor/Arteial line is mandatory. 3-Avoid Nitrous oxide in gas mixture.N2O increase the PVR 4-If MV to be started, avoid High TV and PEEP 5-Avoid Oxytocin Boluses, or rapid administration of Pitocin. Oxytocin causes ...

Lumbar and thoracic epidural in Pediatrics-Technical aspect

The midline approach is most commonly used. The ligamentum   flavum is considerably thinner and less dense in infants than in older children and adults. This makes recognition of engagement in the ligament more difficult and requires both extra care and slower, more deliberate passage of the needle to avoid subarachnoid puncture. The angle of approach to the epidural space is slightly more perpendicular to the plane of the back than in older children and adults, owing to the orientation of the spinous   processes in infants and small children. The loss of resistance technique should be used, but only with saline, not air. There are several reports of venous air embolism in infants and children when air was used to test for loss of resistance Use a short (5 cm) 18-gauge Tuohy needle and a 20- or 21-gauge catheter in infants and children. Epidural kits specifically for infants and children are available Maximum of 0.4 mg/kg/hr of bupivacaine after the initial block is estab...