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Portopulmonary hypertension (POPH) refers to the presence of
pulmonary arterial hypertension (PAH) in patients with portal hypertension.
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Among patients with portal hypertension, reported incidence rates of POPH
range from 2 to 9%.
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Long-term survival in cases of POPH is poor.
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Pulmonary hypertension in patients with liver disease or portal hypertension
can be due to multiple mechanisms:
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► hyperdynamic (high-flow) state
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► increased pulmonary venous congestion
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► vascular constriction or obstruction of the pulmonary arterial bed
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► hyperdynamic (high-flow) state
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Vascular obstruction to pulmonary arterial flow, reflected by increased
pulmonary vascular resistance (PVR), is a key parameter that defines POPH
Anesthesia for Pregnant woman with Pulmonary Hypertension is a real challenge for anesthesiologist. It is very crucial to remember the pathophysiology of pulmonary hypertension in pregnant women and to avoid some practices that will worsen the cardiac status. 1-Avoid single shot spinal anesthesia. Some authorities consider pulmonary hypertension as absolute contraindication for single shot spinal anesthesia specially in patients with NYHA III ,IV. Spinal anesthesia causes major hemodynamic instability(decrease SVR, decrease VR, decrease in CO) The preferred neuroaxial techniques are (epidural anesthesia and CSE with minimal spinal dose) 2-Avoid PAC. Pulmonary Artery catheters insertion may lead to pulmonary artery rupture or thrombosis. TEE is better cardiac monitor/Arteial line is mandatory. 3-Avoid Nitrous oxide in gas mixture.N2O increase the PVR 4-If MV to be started, avoid High TV and PEEP 5-Avoid Oxytocin Boluses, or rapid administration of Pitocin. Oxytocin causes ...
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