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Pulmonary HTN updates ...Portopulmnary HTN


  •   Portopulmonary hypertension (POPH) refers to the presence of
    pulmonary arterial hypertension (PAH) in patients with portal hypertension.
  •   Among patients with portal hypertension, reported incidence rates of POPH range from 2 to 9%.
  •   Long-term survival in cases of POPH is poor.
  •   Pulmonary hypertension in patients with liver disease or portal hypertension can be due to multiple mechanisms:
    • ►  hyperdynamic (high-flow) state
    • ►  increased pulmonary venous congestion
    • ►  vascular constriction or obstruction of the pulmonary arterial bed
  •   Vascular obstruction to pulmonary arterial flow, reflected by increased pulmonary vascular resistance (PVR), is a key parameter that defines POPH 

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