Skip to main content

MV weaning..the numbers and the scores


INDICES THAT PREDICT SUCCESSFUL VENTILATOR DISCONTINUATION
Respiratory rate <30 breaths per minute
Tidal volume >5 ml/kg or >325 mL
FVC <15 mL/kg (predicts success)
Minute ventilation <15 L/min
— Normal 5 – 6 L/min
— Patient unlikely to wean if > 15 L/min
Maximum inspiratory pressure (PImax) < -30 cmH20
— Measure of respiratory muscle strength
— Normal -90 to -120 cmH2O
Rapid shallow breathing index (RSBI) = f/VT <105 b/min/L
— the ratio of respiratory rate : tidal volume
— often used in conjunction with SBT to determine if it should continue
— some evidence that its use in protocols delays ventilator discontinuation
P0.1/PImax > 0.3
— P0.1 is pressure at the airway opening 0.1 s after start of inspiratory flow
— Correlates with central respiratory drive
P0.1 x f/VT <300
CROP index (compliance, respiratory rate, oxygenation, maximum inspiratory pressure index) >13
— Cdyn x PImax x (PaO2/PAO2)/f
— >13 good
— Cdyn = dynamic compliance
IWI (integrative weaning index) >25
— (CRS x SaO2)/(f/VT)
— CRS = static compliance of the respiratory system
CORE index (compliance, oxygenation, rate, effort) >8
— Cdyn x (PImax/P0.1) x (PaO2/PAO2)/f

Comments

Popular posts from this blog

The pressure volume loop...

In the pressure-volume loop below, cardiac work is best represented by:   the area of the curve  the slope of the line from points C to D  the distance of the line from points C to D  the slope of a line from points A to D .. .. ... .... ... .... .... .... In the pressure-volume loop below, cardiac work is best represented by:  the area of the curve Cardiac work is the product of pressure and volume and is linearly related to myocardial oxygen consumption. Cardiac work is best represented by the area of the curve of a pressure-volume loop.

Driving Pressure in ARDS: A new concept!

Driving Pressure and Survival in the Acute Respiratory Distress Syndrome Marcelo B.P. Amato, M.D., Maureen O. Meade, M.D., Arthur S. Slutsky, M.D., Laurent Brochard, M.D., Eduardo L.V. Costa, M.D., David A. Schoenfeld, Ph.D., Thomas E. Stewart, M.D., Matthias Briel, M.D., Daniel Talmor, M.D., M.P.H., Alain Mercat, M.D., Jean-Christophe M. Richard, M.D., Carlos R.R. Carvalho, M.D., and Roy G. Brower, M.D. N Engl J Med 2015; 372:747-755 February 19, 2015 DOI: 10.1056/NEJMsa1410639 BACKGROUND Mechanical-ventilation strategies that use lower end-inspiratory (plateau) airway pressures, lower tidal volumes (V T ), and higher positive end-expiratory pressures (PEEPs) can improve survival in patients with the acute respiratory distress syndrome (ARDS), but the relative importance of each of these components is uncertain. Because respiratory-system compliance (C RS ) is strongly related to the volume of aerated remaining functional lung during disease (termed functional lung size)...

Anaphylaxis updates part 2- Empty Ventricle Syndrome

Patients with anaphylaxis should not suddenly sit, stand, or be placed in the upright position. Instead, they should be placed on the back with their lower extremities elevated or, if they are experiencing respiratory distress or vomiting, they should be placed in a position of comfort with their lower extremities elevated. This accomplishes 2 therapeutic goals: 1) preservation of fluid in the circulation (the central vascular compartment), an important step in managing distributive shock; and 2) prevention of the empty vena cava/empty ventricle syndrome, which can occur within seconds when patients with anaphylaxis suddenly assume or are placed in an upright position. Patients with this syndrome are at high risk for sudden death. They are unlikely to respond to epinephrine regardless of route of administration, because it does not reach the heart and therefore cannot be circulated throughout the body