INDICES THAT PREDICT SUCCESSFUL VENTILATOR DISCONTINUATION
Respiratory rate <30 breaths per minute
Tidal volume >5 ml/kg or >325 mL
FVC <15 mL/kg (predicts success)
Minute ventilation <15 L/min
— Normal 5 – 6 L/min
— Patient unlikely to wean if > 15 L/min
Maximum inspiratory pressure (PImax) < -30 cmH20
— Measure of respiratory muscle strength
— Normal -90 to -120 cmH2O
Rapid shallow breathing index (RSBI) = f/VT <105 b/min/L
— the ratio of respiratory rate : tidal volume
— often used in conjunction with SBT to determine if it should continue
— some evidence that its use in protocols delays ventilator discontinuation
P0.1/PImax > 0.3
— P0.1 is pressure at the airway opening 0.1 s after start of inspiratory flow
— Correlates with central respiratory drive
P0.1 x f/VT <300
CROP index (compliance, respiratory rate, oxygenation, maximum inspiratory pressure index) >13
— Cdyn x PImax x (PaO2/PAO2)/f
— >13 good
— Cdyn = dynamic compliance
IWI (integrative weaning index) >25
— (CRS x SaO2)/(f/VT)
— CRS = static compliance of the respiratory system
CORE index (compliance, oxygenation, rate, effort) >8
— Cdyn x (PImax/P0.1) x (PaO2/PAO2)/f
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