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Brain protection during cardiopulmonary bypass

I would like to share this information with you concerning optimization of cerebral outcome during CPB.

A part of today's SCA 34th Annual Meeting and workshops.




-Temperature
  Monitor brain temperature
  Avoid agressive rewarming
  Avoid hyperthermia


-Avoid excessive hyperglycemia


-Reduce embolic load
 Use alpha-stat ABG to avoid luxary CBF (Patel et al. J Thorac Cardiovasc Surg 1996;111:1267-79)
 CO2 insufflation
 Minimize cardiotomy use (cell saver) (Dgaiani G et al. Circulation 2007;116-1888-1895)



-Atheroma management
 Epiaortic scanning
 Minimize aortic manipulation


-Off-Pump Coronary Artery Bypass -- No reduction in stroke


-Drugs -- Little evidence for efficacy


-CNS monitoring: BIS/EEG, Temperature, MAP/CVP, 
                             Cerebral Oximetry

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