Neurologic Intussusception

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This is a term used to describe an acute abdomen due to intussusception with syncope.





Numerous case reports, retrospective studies, and clinical reviews document prominent neurologic features in the absence of common gastrointestinal symptoms of intussusception. Although lethargy is most common, other neurologic symptoms include apathy, listlessness, hypersomnolence, impaired reaction to painful stimuli, and fluctuating levels of consciousness.

  Neurologic intussusception is particularly common in infants.

The pathophysiology of neurologic intussusception is not well understood. Proposed mechanisms include release of neuropeptides from strangulated bowel, absorption of toxic metabolites, dehydration and electrolyte imbalance as a result of vomiting, and progressive bowel obstruction. It is also possible that neurologic impairment is simply a normal behavioral reaction of an infant to severe abdominal pain.