Radiotherapy and bisphosphonates are effective treatments of acute cancer pain due to bone metastases.
Acute pain in patients with cancer often signals disease progression; sudden severe pain in patients with cancer should be recognised as a medical emergency and immediately assessed and treated.
Cancer patients receiving controlled-release opioids need access to immediate-release opioids for breakthrough pain; if the response is insufficient after 30 to 60 minutes, administration should be repeated.
Breakthrough analgesia should be one-sixth of the total regular daily opioid dose in patients with cancer pain (except when methadone is used, because of its long and variable half life).
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