Skip to main content

CAD and aging





The presence of coronary artery disease (CAD) increases with age.

 Anatomic coronary artery disease can be detected in more than 50% of people older than 70 years of age.

CAD in the aged is more severe and  diffuse than in younger patients.
There are differences in prevalence by gender:
at 65 years of age, CAD is more prevalent in men than in women;
by age 80, the prevalence of symptomatic congestive heart disease is nearly equivalent in men and women.

Despite the high prevalence of anatomic CAD, only 10–20% of people older than 65 years of age carry a diagnosis of active CAD.

One study reported that 37% of elderly patients had subclinical CAD, making it as common as clinically overt CAD in older adults. Furthermore, in this study,
the presence of subclinical CAD was significant as it strongly predicted overt CAD, stroke, and mortality, even after adjustment for traditional cardiovascular risk factors.

Comments

Popular posts from this blog

The 100 essentials in icu and anesthesia

The most visual experience in anesthesia and critical care education  The 100 essentials of anesthesia and critical care  COMING VERY SOON  stay tuned 

Driving Pressure in ARDS: A new concept!

Driving Pressure and Survival in the Acute Respiratory Distress Syndrome Marcelo B.P. Amato, M.D., Maureen O. Meade, M.D., Arthur S. Slutsky, M.D., Laurent Brochard, M.D., Eduardo L.V. Costa, M.D., David A. Schoenfeld, Ph.D., Thomas E. Stewart, M.D., Matthias Briel, M.D., Daniel Talmor, M.D., M.P.H., Alain Mercat, M.D., Jean-Christophe M. Richard, M.D., Carlos R.R. Carvalho, M.D., and Roy G. Brower, M.D. N Engl J Med 2015; 372:747-755 February 19, 2015 DOI: 10.1056/NEJMsa1410639 BACKGROUND Mechanical-ventilation strategies that use lower end-inspiratory (plateau) airway pressures, lower tidal volumes (V T ), and higher positive end-expiratory pressures (PEEPs) can improve survival in patients with the acute respiratory distress syndrome (ARDS), but the relative importance of each of these components is uncertain. Because respiratory-system compliance (C RS ) is strongly related to the volume of aerated remaining functional lung during disease (termed functional lung size)...