Postcholecystectomy syndrome—the recurrence of symptoms similar to those before the procedure.
Occurs in 10% to 40% of patients.
The time to the onset of symptoms can range from 2 days to up to 25 years.
Women may be at higher risk, with symptoms recurring in 43% vs 28% in men.
Postcholecystectomy syndrome can have a biliary or a nonbiliary cause.
Biliary causes include strictures, retained calculi, dropped calculi, tumors, sphincter of Oddi dysfunction, and calculi in the cystic duct remnant.
Nonbiliary causes include functional and organic disorders such as peptic ulcer disease, gastroesophageal reflux, pancreatic disease, hepatocellular disorders, coronary artery disease, irritable bowel syndrome, and intercostal neuritis.
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