It is well Known that lidociane alleviate propofol injection pain.But many questions still un answered, What is the adequate dose? The proper timing ?
A review of the published studies suggested that injecting lidocaine with a proximal tourniquet provided the highest efficacy.
The authors recommended that “IV lidocaine (0.5 mg/kg) should be given with a rubber tourniquet on the forearm, 30 to 120 seconds before the injection of propofol.”
This method was superior to mixing lidocaine with propofol, which itself was superior to giving lidocaine without a tourniquet prior to injecting the propofol.
Picard P, Tramèr MR. Prevention of pain on injection with propofol: a quantitative systematic review. Anesth Analg 2000; 90:963–969
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