Acetaminophen Toxicity "150" Rule

Acetaminophen Toxicity  "Rule of 150":

• The toxic ingestion dose of acetaminophen is 150 mg/kg.
• The serum acetaminophen level when N-acetylcysteine treatment should be started is 150 mcg/mL (see Rumack Matthew nomogram)
• The starting IV dose of N-acetylcysteine is 150 mg/kg over 15 minutes.