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Some of Hypothermia lethal effects

Increased Infection Risk

2-fold risk with 2C drop

Increase in Blood Loss/Transfusions

EBL increased 500 cc with 1.6C drop

Increased Cardiac Morbidity

NOT due to shivering, possibly arrhythmias, hypertensive response to stress of cold  . Normothermia associated with a 55% reduction in cardiac risk

Increased Anesthetic Potency

MAC drops 15% for every 1.0C. Vecuronium, atracurium prolonged by up to 60%


Kurz A et al. NEJM 334: 1209, 1996
Frank SM et al. JAMA 277: 1127, 1997
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