Fentanyl Patch disadvantages

Transdermal opioids  Patch is very useful for patients with poor oral intake and it is better in terms of patient compliance

However it holds some disadvantages,

1-only one drug is available(Fentanyl)

2-increased absorption in case of fever

3-slow onset action

4-need for alternative in Breakthrough pain,(not good choice in the rapid fluctuating pain)

5-difficult to deliver higher dose